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GLP-1

Compare Weight Loss Injections 2025

Compare top weight-loss injections including Ozempic®, Wegovy®, GLP-1 injectables, and other popular weight-loss medications.

Editor's Choice - March 2025
MOST POPULAR
1

Remedy Meds

9.8
Excellent
Free 2-minute quiz to get pre-approved, no insurance needed
Same active ingredient as Ozempic®, Wegovy®, Zepbound®
Forbes Special: $100 OFF with code Forbes2025
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2

Saxenda

Liraglutide
4.7
Good
FDA approved for chronic weight management
5% or greater weight loss results
Proven appetite suppression
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3

Wegovy

Semaglutide
4.8
Good
Weekly self-injection (GLP-1 receptor)
Up to 15% body weight reduction
Similar to Ozempic but specifically approved for weight loss
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4

Qsymia

Phentermine-Topiramate
4.5
Good
Combination of appetite suppressant and seizure medication
Reduced food cravings and hunger
FDA approved for long-term use
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5

Orlistat

Xenical/Alli
4.3
Good
Prevents fat absorption in intestines
Available as prescription (Xenical) or over-the-counter (Alli)
Long safety record
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Editor's Choice - March 2025

The easiest weight loss program ever, delivered to your door

Join 40,000+ weight loss patients

Doctor approval after an easy 90-sec-ond quiz

Both oral and injectable GLP-1 plans available

No Insurance required. No Waitlist. No Hidden Fees

Lose up to 33 pounds in 4 months

NEXT STEP
MOST POPULAR
1

Remedy Meds

1

Mounjaro

Tirzepatide

4.9/5
(124 reviews)
  • First FDA-approved GLP-1 and GIP dual agonist for type 2 diabetes
  • Proven to help you lose up to 22.5% of body weight in clinical trials
  • Recent studies show best weight loss results among all medications
2

Saxenda

Liraglutide

4.7/5
(89 reviews)
  • FDA approved for chronic weight management
  • 5% or greater weight loss results
  • Proven appetite suppression
3

Wegovy

Semaglutide

4.8/5
(112 reviews)
  • Weekly self-injection (GLP-1 receptor)
  • Up to 15% body weight reduction
  • Similar to Ozempic but specifically approved for weight loss
4

Qsymia

Phentermine-Topiramate

4.5/5
(95 reviews)
  • Combination of appetite suppressant and seizure medication
  • Reduced food cravings and hunger
  • FDA approved for long-term use
5

Orlistat

Xenical/Alli

4.3/5
(78 reviews)
  • Prevents fat absorption in intestines
  • Available as prescription (Xenical) or over-the-counter (Alli)
  • Long safety record
6

Zepbound

Tirzepatide

4.6/5
(65 reviews)
  • New FDA-approved version of Mounjaro
  • Once-weekly injection
  • Specifically approved for weight loss
7

Rybelsus

Oral Semaglutide

4.4/5
(72 reviews)
  • Works similarly to Wegovy/Ozempic
  • Available as a daily pill instead of injection
  • First oral GLP-1 receptor
8

Plenity

Gelesis100

4.2/5
(68 reviews)
  • Not technically a medication
  • FDA-cleared as a device in pill form
  • Expands in stomach to help you feel full
9

Naltrexone-Bupropion

Contrave

4/5
(83 reviews)
  • Combination anti-addiction and antidepressant medication
  • Works on brain pathways associated with hunger and cravings
  • Moderate weight loss results
10

Phentermine

Adipex-P, Lomaira

3.7/5
(96 reviews)
  • Short-term appetite suppressant
  • One of the oldest weight loss medications still in use
  • Approved only for short-term use

Frequently Asked Questions

What are GLP-1 weight loss medications?

GLP-1 medications like Ozempic®, Wegovy®, Mounjaro®, and Zepbound® are prescription drugs originally developed to treat type 2 diabetes. They work by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that regulates blood sugar and appetite. These medications help reduce hunger, increase feelings of fullness, and slow gastric emptying, which can lead to significant weight loss.

How much weight can I lose with weight loss injections?

Clinical trials have shown that people taking GLP-1 medications can lose approximately 15-20% of their body weight over 12-16 months. Individual results vary based on factors such as starting weight, diet, exercise habits, and medication dosage. Many users report losing 1-2 pounds per week after the first month of treatment.

Are GLP-1 medications covered by insurance?

Insurance coverage for GLP-1 medications varies. When prescribed specifically for weight loss (rather than diabetes), many insurance plans do not cover these medications. However, some plans may cover them with prior authorization if you meet specific criteria. Telehealth providers like those featured in our rankings offer these medications without requiring insurance, though often at a higher out-of-pocket cost.

Ready to start your weight loss journey?

Join thousands of patients who have successfully lost weight with GLP-1 medications. Take the first step today!

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